This presentation will help consultants, cotton producers, and other practitioners in the cotton growing regions of the U.S. where nematodes effect cotton production. Management of plant parasitic nematodes involves use of nematicides, germplasm with resistant genes, and crop rotation. However, the specific management options change for different nematode species and population densities, different yield goals, different cropping systems, and differing levels of soil variability. At the end of this presentation, the practitioner should have a good understanding of what management options should be used for specific situations.