Brown stem rot (BSR) is a significant disease of soybean in the Northcentral U.S. BSR is caused by a soilborne fungal pathogen. Infection occurs early in the season but symptoms typically don’t develop until pod-fill stages later in the season. Brown discoloration of the stem pith and chlorosis and necrosis between leaf veins are symptoms of BSR, although the leaf symptoms do not always develop. BSR is managed with crop rotation and by using soybean varieties with resistance to BSR.