The presentation focuses on data from Midwestern states, but the principles for comparing the technologies is appropriate for growers, consultants, and other crop professionals in all states. The first generation of Roundup Ready® (RR1) soybeans were released in 1996 and the second generation (RR2) was released in 2009. The yields of RR2 are said to be 7 to 11% higher than RR1 with mixed findings in the field. This presentation aims to level the playing field for appropriate comparisons between RR1 and RR2 varieties. The effects of geography, maturity group, and seed treatments are discussed for improved decisions in variety selection.