Root-knot nematodes are a major economic pest in soybeans in the southern U.S. Meloidogyne incognita (southern root-knot) is the most widespread, but M. arenaria (peanut root-knot) is also common where peanut is also produced. Many factors including soil type, soybean cultivar, and nematode population density influence the yield loss potential. Management strategies include using resistant soybean cultivars, rotating to poor or non-host crops periodically, and in some cases, the application of nematicides.