This presentation will help consultants, growers, and other practitioners better understand the basic principles of fungicide resistance. This presentation discusses the different factors involved in fungicide resistance, how it may occur, and which characteristics of fungal plant pathogens and fungicides lead to greater risks of fungicide resistance occurring. A case example of fungicide resistance in the frogeye leaf spot pathogen of soybean (Cercospora sojina) is discussed, along with practices that can be utilized to manage fungicide resistance.